Fibrinogen alpha Chain (FGA) (Middle Region) Peptid
FGA
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN976821
Kurzübersicht für Fibrinogen alpha Chain (FGA) (Middle Region) Peptid (ABIN976821)
Target
FGA
(Fibrinogen alpha Chain (FGA))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-FGA antibody (Catalog #: ARP41759_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Aufreinigung
- Purified
-
-
-
-
Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Konzentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- FGA (Fibrinogen alpha Chain (FGA))
-
Hintergrund
-
FGA is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus.
Alias Symbols: Fib2, MGC119422, MGC119423, MGC119425
Protein Interaction Partner: BAT2,CDH5,F13A1,F2,FGA,FGB,FGG,HRG,ITGA2B,ITGB3,NID1,PLAT,SERPINA5,SERPINF2,THBS1,BAT2,CDH5,F13A1,F2,FGA,FGB,FGG,HRG,KHDRBS2,NID1,PLAT,THBS1
Protein Size: 644 -
Molekulargewicht
- 66 kDa
-
Gen-ID
- 2243
-
NCBI Accession
- NM_021871, NP_068657
-
UniProt
- Q4QQH7
Target
-
Sie sind hier:
